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Drop(Nanjing)Bio-Tech

DropPrev® HAP | Hydroxyacetophenone

DropPrev® HAP | Hydroxyacetophenone

Regular price $74.00 USD
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DropPrev® HAP is a naturally derived ingredient with anti-corrosion, anti-bacterial, and antioxidant properties, making it a versatile and effective component in cosmetic formulations. It is found in the stems and leaves of marina artemisia and the roots of plants like artemisia capillaris and tylophora kerrii. DropPrev® HAP is known for its broad-spectrum antiseptic abilities, soothing effects, and excellent compatibility with other raw materials. It serves as an alternative to traditional preservatives, offering enhanced system stability.

INCI Name: Hydroxyacetophenone
Trade Name: DropPrev® HAP
CAS Number: 99-93-4
Chemical Formula: C8H8O2


Benefits

  1. Broad-Spectrum Antimicrobial Activity:

    • Effectively inhibits common microbial strains including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, and Aspergillus brasiliensis.
  2. Antioxidant Protection:

    • Neutralizes free radicals to protect formulations and maintain product efficacy.
  3. Soothing and Calming Effects:

    • Reduces skin irritation, making it suitable for sensitive formulations.
  4. Formulation Stability:

    • Enhances system stability by resisting microbial contamination without causing conflicts with other ingredients.
  5. Eco-Friendly and Gentle:

    • A mild, non-irritating alternative to synthetic preservatives.

Suggested Usage

  • Concentration: 0.1%–0.5%
  • Applications:
    • Emulsifying systems like creams and emulsions.
    • Surfactant-based products such as cleansers and shampoos.
  • Method of Incorporation:
    • Add during the emulsification or cooling phase.
    • Ensure proper mixing for uniform distribution.

Clinical Studies

  1. Antimicrobial Efficacy:

    • MIC (Minimum Inhibitory Concentration) tests show effective inhibition of key microbial strains:
      • Escherichia coli (EC): 0.25%
      • Pseudomonas aeruginosa (PA): 0.25%
      • Staphylococcus aureus (SA): 0.5%
      • Candida albicans (CA): 0.25%
      • Aspergillus brasiliensis (AB): 0.125%
  2. Skin Compatibility:

    • Demonstrated excellent skin tolerance, making it suitable for sensitive skin products.

Cautions

  • pH and Temperature Stability:

    • Works effectively in formulations with a pH range of 4–8.
    • Stable below 80°C; avoid excessive heat during processing.
  • Storage:

    • Keep sealed and store at room temperature, away from light and moisture.

Specification

  • Appearance: White or off-white crystalline powder
  • Assay (HPLC): ≥99.0%
  • Melting Point: 108–110°C
  • Water Content: ≤0.5%
  • Heavy Metals (Pb): <20.0 mg/kg
  • Residual Solvent: <0.02%

Packaging and Shelf Life

  • Packaging: Provided in suitable sealed containers.
  • Shelf Life: 2 years under recommended storage conditions.

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