DropBrigt® PT40 | Glycyrrhiza Glabra (Licorice) Root Extract

DropBright® PT40 is a natural flavonoid-rich extract derived from licorice root (Glycyrrhiza glabra), known for its potent whitening, antioxidant, and anti-inflammatory properties. The active ingredient, Glabridin, effectively inhibits melanin production by targeting tyrosinase and dopachrome tautomerase (TRP-2) activity. It also protects the skin from free radical damage and prevents oxidative stress-related skin aging. DropBright® PT40 is suitable for advanced skin-brightening and anti-aging formulations.

INCI Name: Glycyrrhiza Glabra (Licorice) Root Extract
CAS Number: 84775-66-6
Function: Whitening, Antioxidant, Anti-inflammatory
EWG Score: 1 (Low Hazard)

Benefits

1. Potent Whitening Effect:

   • Inhibits tyrosinase activity, reducing melanin production for brighter skin.
   • Targets dopachrome tautomerase (TRP-2) to enhance skin tone uniformity.

2. Antioxidant Protection:

   • Scavenges free radicals to prevent oxidative damage to cell walls and biological macromolecules.
   • Protects against oxidative stress-related issues such as cell aging and atherosclerosis.

3. Anti-Inflammatory and Antibacterial:

   • Soothes skin inflammation and prevents roughness.
   • Exhibits antibacterial properties, reducing irritation and redness.

4. Highly Bioavailable:

   • Penetrates deep into the skin and retains high activity for long-lasting results.

Suggested Usage

• Concentration: 0.05%–0.2%
• Applications:
  • Whitening creams and serums.
  • Anti-aging skincare formulations.
• Method of Incorporation:
  • Dissolve in alcohol during formulation.
  • Avoid exposure to high temperatures during processing to maintain efficacy.

Features

• Plant-derived ingredient with a mild, yet effective whitening function.
• Strong antioxidant properties prevent damage from free radicals.
• Compatible with alcohol-based formulations.

Physicochemical Properties

• Appearance: Yellow-brown powder
• Assay (HPLC): 37.0%–43.0%
• Test for Flavone: Positive
• Residual Methanol: ≤2000 mg/kg
• Heavy Metals (Pb): ≤10 mg/kg
• Arsenic (As): ≤2 mg/kg

Microbial Limits:

• Total Plate Count: ≤100 cfu/g
• Yeast & Mold: ≤100 cfu/g
• Staphylococcus aureus: Negative
• Salmonella: Negative
• E. coli: Negative

Cautions

• Storage:
  • Store in a sealed container at room temperature, away from light and moisture.

Packaging and Shelf Life

• Packaging: Available in bulk or customized packaging options.
• Shelf Life: 2 years under recommended storage conditions.