DropBrigt® DL-MA | Mandelic Acid

DropBright® DL-MA is a gentler alpha hydroxy acid (AHA) specifically designed for sensitive skin. Derived from aromatic compounds, mandelic acid has a larger molecular weight than other AHAs like glycolic acid, allowing for slower skin penetration and reduced irritation. It offers whitening, anti-acne, and exfoliation properties, making it ideal for various skincare applications. Its ability to inhibit tyrosinase activity and promote mild exfoliation helps even skin tone and reduce post-inflammatory pigmentation (PIH).

INCI Name: Mandelic Acid
CAS Number: 90-64-2
Molecular Formula: C8H8O3
Function: Whitening, Anti-Acne, Exfoliation
EWG Score: 1 (Low Hazard)

Benefits

1. Whitening Properties:

   • Effectively inhibits tyrosinase activity, reducing melanin synthesis and brightening skin tone.
   • EC50 value of 0.274 mg/mL for tyrosinase inhibition.

2. Anti-Acne Efficacy:

   • Antibacterial properties combat acne-causing bacteria and prevent future breakouts.
   • Reduces active acne lesions and post-acne pigmentation with minimal side effects.

3. Gentle Exfoliation:

   • Removes dead skin cells, promoting smoother and more even skin texture.
   • Induces slower, safer exfoliation compared to glycolic acid, with reduced erythema and photosensitivity.

4. Anti-Aging and Skin Repair:

   • Improves skin texture, reduces wrinkles, and fades freckles and chloasma.
   • Accelerates recovery after laser resurfacing and chemical peels.

5. Antioxidant Power:

   • Exhibits stronger reducing ability than malic and lactic acids, helping combat oxidative stress.

Suggested Usage

• Concentration:
  • Daily Use: 0.5%–4.0%
  • Special Use: 4.0%–15.0%
  • Maximum Allowed Amount: 25%
• Applications:
  • Whitening and anti-acne creams, serums, and lotions.
  • Chemical peels for sensitive skin.
• Method of Incorporation:
  • Soluble in water; compatible with acidic systems.
  • Maintain formulation pH and avoid incompatibilities with strongly alkaline ingredients.

Features

• Mild AHA suitable for sensitive skin.
• Reduces post-inflammatory pigmentation (PIH) and evens skin tone.
• Larger molecular weight ensures slower absorption and reduced irritation.
• Approved for safety with no skin or eye irritation.

Physicochemical Properties

• Appearance: White crystalline powder
• Assay (Dry Basis): ≥99.0%
• Transmittance (10% in Water): ≥90%
• Turbidity (NTU): <20
• Melting Point: 117–121°C
• Water Content (KF): ≤0.5%

Cautions

• Storage:
  • Store under sealed conditions at room temperature, away from light and moisture.
• Solubility:
  • Water-soluble; ensure proper dissolution in formulations for uniform efficacy.

Packaging and Shelf Life

• Packaging: 10 kg containers (customizable options available).
• Shelf Life: 2 years under recommended storage conditions.